If you are running Windows Vista, you should consider applying these two updates from Microsoft.
First is the December 2007 Windows Vista Application Compatibility Update that fixes lots of issues with 3rd party and Microsoft applications. Second is "An update that improves the performance, responsiveness, and reliability of Windows Vista is available", which fixes issues with hibernation and improves disk I/O performance (by up to 15%).
Windows Vista continues to improve and mature.
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